Laser Assisted Direct Write Bioprinting to Model Nueral Circuits

Direct write patterning of neurons to model functional neural circuits

Abstract:

Brain function is based on cell circuit plasticity and underlying synaptic communication within and between brain areas. The ability to fabricate highly specific patterns of neuronal cells and study changes in structural and functional physiology could allow mechanistic approaches to ascertaining fundamental neurobiology. Laser direct write advantages in spatial accuracy and cellular specificity have so far been underutilized for neural applications, despite the apparent need. Highly specific printed neuronal circuits has the potential to ascertain numerous molecular, genetic, activity-dependent, and pharmacologic processes and their effects on synaptic communication and circuit function.

- Lowry Curley

Collaborators:

Michael J. Moore, Ph.D. (Moore Research Group)
Department of Biomedical Engineering, Tulane Univeristy